Proteins
Proteins are complex biomolecules essential for numerous biological functions. This page focuses on the structure and properties of proteins, particularly their building blocks, amino acids.
Definition: Proteins are large, complex molecules composed of chains of amino acids, which perform a wide variety of functions in living organisms.
Amino acids, the monomers of proteins, have a general structure consisting of:
- An amino group (-NH2)
- A carboxyl group (-COOH)
- A variable R group (side chain)
Vocabulary: The R group in an amino acid determines its unique properties and influences the overall structure and function of the protein.
Proteins are formed through the linking of amino acids via peptide bonds:
Definition: A peptide bond is a covalent bond formed between the carboxyl group of one amino acid and the amino group of another, releasing a water molecule in the process.
The structure of proteins can be described at four levels:
- Primary structure: The sequence of amino acids
- Secondary structure: Local folded structures (e.g., alpha helices, beta sheets)
- Tertiary structure: Overall three-dimensional shape of a single protein molecule
- Quaternary structure: Arrangement of multiple protein subunits
Highlight: The three-dimensional structure of a protein is crucial for its function, and any disruption to this structure can lead to a loss of functionality.
Denaturation is a process that can disrupt protein structure:
Definition: Denaturation is the process by which proteins lose their shape and, consequently, their function due to external factors such as high temperature or changes in pH.
Understanding protein structure and function is essential for comprehending their roles in biological processes, including enzymatic reactions, cellular signaling, and structural support.